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(Senior) Scientist - High Throughput Screening

(Senior) Scientist - High Throughput Screening

Ryvu Therapeutics S.A.Kraków, małopolskie, Polska
11 days ago
Job description

Senior) Scientist - High Throughput Screening

108_131

Obowiązki

  • Assistance in the design and construction of the HTS platform
  • Developing target-relevant biochemical and cell-based assays including optimization, validation and troubleshooting (screening assay robustness, sensitivity, reproducibility)
  • Evaluation of the novel cell-based screening initiatives for implementation into the group portfolio
  • Converting assays into HTS format - assay miniaturization to 384-well / 1536-well format
  • Design and implementation of the key in vitro pharmacology experiments for low-throughput compound profiling (efficacy, selectivity, mechanism of action)
  • Performing HT screens and hit identification
  • Statistical analysis, reporting and critical data evaluation for providing a scientific contribution to internal drug discovery projects
  • Ensuring all tasks and responsibilities are performed according to industry-leading scientific and ethical standards and accurately documented in the lab electronic notebook system

Wymagania

  • MSc in pharmacology, molecular biology, biotechnology or similar discipline with minimum 2 years of experience in a biotech / pharma setting or Ph.D. in relevant biological sciences
  • Good knowledge of in vitro pharmacology concepts with a strong focus on at least one of the following areas : intracellular signaling, cancer metabolism, immunology, CNS
  • Experience in working with cell lines and cell-based assays in microplate format
  • Prior experience with mid-to-high throughput screening, liquid handling devices and lab automation will be a plus
  • Analytical and problem-solving skills with proven troubleshooting experience
  • Well-developed multi-tasking, flexibility and team working skills
  • scientific presentation and interpersonal communication skills
  • Fluency in English
  • Oferujemy

  • Working in world-class extensive research facilities and modern laboratories.
  • Daily cooperation and know-how exchange with scientific experts.
  • Additional benefits : a prepaid lunch card, private medical care, subsidized sports card, and office fruit provision.
  • Internal Development initiatives including soft & leadership skills training programs.
  • Recognition Program.
  • Employee Referral Program.
  • English & Polish language courses.
  • Support & incentive bonus for completing Ph.D.
  • Support in legalization process and relocation package.
  • Various sports and engagement initiatives.
  • ródło : Selvita / Praca

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    Senior Scientist • Kraków, małopolskie, Polska